High-grade glioma

Dr Henry Knipe and Assoc Prof Frank Gaillard et al.

High-grade glioma is a relatively vague term, and in some ways is best avoided, unless one deliberately wants to be vague/inclusive. It has often (especially in older literature) been used to denote both anaplastic gliomas (WHO grade III) and glioblastomas (WHO grade IV), always including astrocytomas, but variably also including oligodendrogliomas, oligoastrocytomas, and ependymomas.

In more recent times, its meaning has at times narrowed to refer primarily to glioblastomas, but this is far from universally accepted.

As such it is best, when wanting to be precise, to use WHO classification terminology. 


Article information

rID: 30759
Synonyms or Alternate Spellings:
  • High-grade gliomas

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