Hughes-Stovin syndrome

Hughes-Stovin syndrome (HSS) is a vasculitis that predominantly affects large vessels. The disease bears some resemblance to Behcet disease.

It occurs predominantly between the 2nd to 4th decades. There is a recognised male predilection. 

Typically affects pulmonary, and frequently bronchial, arteries and large systemic veins. 

Typically disease is clinically characterised 3 phases 5:

  • stage I: thrombophlebitis
  • stage II: formation and enlargement of pulmonary aneurysms
  • stage III: aneurysmal rupture 

Exact features will depend on the stage. May show:

  • massive pulmonary haemorrhage (stage III): from a rupture of a pulmonary arterial aneurysm; often a terminal event 4.

It is named after J P Hughes and P G Stovin who first described the condition in 1959 6.

General imaging differential considerations include:

Share article

Article information

rID: 12482
System: Vascular
Synonyms or Alternate Spellings:
  • Hughes Stovin syndrome
  • Hughes Stovin syndrome (HSS)
  • HSS

Support Radiopaedia and see fewer ads

Updating… Please wait.

Alert accept

Error Unable to process the form. Check for errors and try again.

Alert accept Thank you for updating your details.