Intrarenal reflux (IRR) involves intrarenal extension of vesicoureteral reflux (VUR) into the tubular system of the kidney.
IRR occurs in 3-10% of cases and can lead to renal injury, which may eventually result in renal scarring. The condition can be diagnosed by micturating cystourethrography (MCUG). It is the main cause of renal injury in patients with VUR.
MCUG is the main diagnostic tool for IRR. However, according to Darge et al 2, contrast-enhanced harmonic ultrasonography can facilitate the diagnosis along with avoidance of radiation exposure.
- 1. Kim SW, Im YJ, Hong CH et-al. The Clinical Significance of Intrarenal Reflux in Voiding Cystourethrography (VCUG). Korean J Urol. 01;51 (1): 60-3. doi:10.4111/kju.2010.51.1.60 - Free text at pubmed - Pubmed citation
- 2. Darge K, Trusen A, Gordjani N et-al. Intrarenal reflux: diagnosis with contrast-enhanced harmonic US. Pediatr Radiol. 2003;33 (10): 729-31. doi:10.1007/s00247-003-1050-2 - Pubmed citation