Low phospholipid-associated cholelithiasis syndrome

Dr Henry Knipe et al.

Low phospholipid-associated cholelithiasis (LPAC) syndrome is one of the syndromes associated with ABCB4/MDR3 mutation. Characteristics of this syndrome include 1,2:

  • intrahepatic microlithiasis/sludge
  • symptomatic cholesterol stones with early onset (<40 years)
  • recurrent symptoms post cholecystectomy
  • successful treatment (i.e. symptom resolution) with ursodeoxycholic acid (UDCA)
Share article

Article information

rID: 52070
Section: Syndromes
Tag: cases, stub
Synonyms or Alternate Spellings:
  • LPAC

Support Radiopaedia and see fewer ads

Updating… Please wait.

Alert accept

Error Unable to process the form. Check for errors and try again.

Alert accept Thank you for updating your details.