Citation, DOI, disclosures and article data
Citation:
Knipe H, Hacking C, Yip H, et al. Multiple endocrine neoplasia type IV. Reference article, Radiopaedia.org (Accessed on 19 Feb 2025) https://doi.org/10.53347/rID-56653
Disclosures:
At the time the article was last revised Craig Hacking had the following disclosures:
- Philips Australia, Paid speaker at Philips Spectral CT events (ongoing)
These were assessed during peer review and were determined to
not be relevant to the changes that were made.
View Craig Hacking's current disclosures
Multiple endocrine neoplasia type IV (MEN4), previously known as MENX, is a rare type of MEN with clinical overlap with MEN1 but is due to a CDKN1B mutation. It is characterized by 1,2:
Epidemiology
The estimated prevalence of MEN4 is less than 1 per 1,000,000 and there is a strong female predilection 3.
See also
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1. Thakker RV. Multiple endocrine neoplasia type 1 (MEN1) and type 4 (MEN4). Molecular and cellular endocrinology. 386 (1-2): 2-15. doi:10.1016/j.mce.2013.08.002 - Pubmed
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2. Alrezk R, Hannah-Shmouni F, Stratakis CA. MEN4 and CDKN1B mutations: the latest of the MEN syndromes. Endocrine-related cancer. 24 (10): T195-T208. doi:10.1530/ERC-17-0243 - Pubmed
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3. Singeisen H, Melanie Renzulli M, Pavlicek V et al. Multiple Endocrine Neoplasia Type 4: A New Member of the MEN Family. Endocrine Connections. 2023;12(2). doi:10.1530/ec-22-0411
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