Opsomyoclonus (dancing eyes-dancing feet syndrome) is a clinical syndrome which has strong association with neuroblastoma.

Clinical presentation

The “opso-“ refers to the presence of intermittent jerky eye movements (dancing eyes) and the “myoclonus” to myoclonic jerks and cerebellar ataxia (dancing feet).  Although only 2% of patients with neuroblastoma present with opsomyoclonus, up to 50% of patients with opsomyoclonus are ultimately found to have a neuroblastoma1.

The implication is that a child found to have opsomyoclonus must be investigated thoroughly for an otherwise occult neuroblastoma.

Treatment and prognosis

If a neuroblastoma is found in a patient with opsomyoclonus, it is generally small with relatively favourable histology and the prognosis, in terms of survival, is very good. The neurologic symptoms may be treated with corticosteroids and/or ACTH, but often persist despite the medical treatment and surgical resection 2.

Share article

Article Information

rID: 12620
Synonyms or Alternate Spellings:
  • Opsoclonus
  • Opsoclonus myoclonus
  • Dancing eyes dancing feet syndrome
  • Dancing eyes syndrome (DES)

Support Radiopaedia and see fewer ads

Cases and Figures

  • Drag
    TruFISP Coronal

    Neuroblastoma : presented with opsomyoclonus
    Drag here to reorder.
  • Updating… Please wait.

    Alert accept

    Error Unable to process the form. Check for errors and try again.

    Alert accept Thank you for updating your details.