Pulmonary oedema following administration of cytokines
Pulmonary oedema following administration of cytokines is a rare cause of non-cardiogenic pulmonary oedema. It has been reported to occur with various cytokines inclusive of Interleukin 2. The mechanism in the case of interleukin 2 it is thought to be related to an increase in pulmonary capillary permeability 2.
- 1. Berthiaume Y, Boiteau P, Fick G et-al. Pulmonary edema during IL-2 therapy: combined effect of increased permeability and hydrostatic pressure. Am. J. Respir. Crit. Care Med. 1995;152 (1): 329-35. doi:10.1164/ajrccm.152.1.7599842 - Pubmed citation
- 2. Saxon RR, Klein JS, Bar MH et-al. Pathogenesis of pulmonary edema during interleukin-2 therapy: correlation of chest radiographic and clinical findings in 54 patients. AJR Am J Roentgenol. 1991;156 (2): 281-5. doi:10.2214/ajr.156.2.1898799 - Pubmed citation