Sandal gap deformity
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A sandal gap deformity, also known as hallux varus, is an imaging observation in antenatal ultrasound (typically second trimester) where there is an expanded first interspace, i.e. the gap between the great toe of the foot from the rest of the toes (likened to the gap caused by a sandal).
While it can be a normal variant (especially when it is the only finding) it is also sometimes considered a soft marker for other fetal anomalies.
Recognized associations include
At least 40 other rare conditions have also been associated with this anomaly 6.
For an unusually wide gap between the 1st and 2nd toe on antenatal ultrasound consider
- 1. Ryu JK, Cho JY, Choi JS. Prenatal sonographic diagnosis of focal musculoskeletal anomalies. Korean J Radiol. 4 (4): 243-51. Korean J Radiol (link) - Free text at pubmed - Pubmed citation
- 2. Smith-bindman R, Hosmer W, Feldstein VA et-al. Second-trimester ultrasound to detect fetuses with Down syndrome: a meta-analysis. JAMA. 2001;285 (8): 1044-55. doi:10.1001/jama.285.8.1044 - Pubmed citation
- 3. Devlin L, Morrison PJ. Accuracy of the clinical diagnosis of Down syndrome. Ulster Med J. 2004;73 (1): 4-12. - Free text at pubmed - Pubmed citation
- 4. Guidelines on soft markers from the RCOG : www.rcogcourses.org.uk/topics/soft%20ultrasound%20markers.pdf
- 5. Alomari AI. Characterization of a distinct syndrome that associates complex truncal overgrowth, vascular, and acral anomalies: a descriptive study of 18 cases of CLOVES syndrome. (2009) Clinical dysmorphology. 18 (1): 1-7. doi:10.1097/MCD.0b013e328317a716 - Pubmed
- 6. NCBI MedGen Library. Sandal Gap. MedGen UID: 374376. Concept ID: C1840069. Accessed on 03/02/2020 on https://www.ncbi.nlm.nih.gov/medgen/374376.