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Oligoastrocytoma NOS

Case contributed by Frank Gaillard
Diagnosis certain
ct
This study is a stack
Axial
non-contrast
This study is a stack
Axial C+
delayed
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Info

A large hemorrhagic heterogeneously enhancing mass in the right temporal lobe is present with significant mass effect. 

Case Discussion

Oligoastrocytoma (NOS) - histologically proven.

NOTE: This case predates the 2016 WHO classification of CNS tumor revision. As no 1p19q co-deletion status is available a formal diagnosis cannot be reached and the NOS is therefore used (not otherwise specified) - which is recognized in the current classification for cases where molecular information is unavailable. It should also be noted, that under the new classification both an astrocytic and oligodendroglial component needs to be identified, each with its own molecular markers. True oligoastrocytomas are therefore going to be rare, and this case would most likely be classified as either an astrocytoma or an oligodendroglioma. 

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