Diffuse pontine glioma

Case contributed by Dr Ahmed Abd Rabou

Presentation

Impaired hearing, recurrent choking and headache of 1 month duration

Patient Data

Age: 4 years old
Gender: Female
Modality: MRI

The pons is diffusely enlarged encasing the basilar artery and exhibits altered signal being low in T1, slightly bright in FLAIR and very bright in T2 WIs. No diffusion restriction on DWI differentiating this lesion from acute pontine infarction.

Case Discussion

Features consistent of diffuse pontine glioma (histopathologically proved). Although information on the molecular characteristics of this tumour is not available, it is likely that it represents a diffuse midline glioma H3 K27M–mutant.

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Case Information

rID: 22777
Case created: 22nd Apr 2013
Last edited: 24th Apr 2017
Inclusion in quiz mode: Included

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