Pilocytic astrocytoma

Case contributed by Dr Abdallah Khateeb

Presentation

Ataxia, vomiting, and papilloedema.

Patient Data

Age: 20-month-old
Gender: Male
MRI

MRI Brain

Large cystic mass at the right posterior fossa with peripheral thick nodular enhancement. 

Significant mass effect on the cerebellum and the fourth ventricle, crowded foramen magnum, signs of obstructive hydrocephalus and trans ependymal oedema. 

Case Discussion

The patient underwent surgical resection of the tumour.

HISTOPATHOLOGY

Microscopic description: Bi-phasic growth pattern of alternating microcystic and more compact cellular areas. The cells exhibit hair-like processes embedded in a fibrillary background. No evidence of atypia, nuclear pleomorphism, necrosis or increased mitosis is seen. Those glial cells are strongly positive for GFAP immunostatins, Ki-67 proliferative index is estimated at 3%.

Diagnosis: Pilocytic astrocytoma - WHO grade I.

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Case information

rID: 45608
Case created: 31st May 2016
Last edited: 2nd Jun 2016
Inclusion in quiz mode: Included

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