Pulmonary hamartoma

Case contributed by Dr Mikkaela McCormack


A 30-year-old woman came through the Emergency Department with symptoms of pneumonia. A chest x-ray revealed an incidental 2cm nodule within the right lung. An excisional biopsy was performed.

Patient Data

Age: 30
Gender: Female

The section shows alveolated lung parenchyma with a solitary, well-circumscribed, nodule showing a lobulated architecture and composed of cytologically bland mature chondroid and adipose tissue.  There is no evidence of atypia or malignancy and the lesion was clear of the pathological margin. 

Case Discussion

This was a classic incidental presentation of a benign, hamartomatous lesion, with a characteristic lobulated architecture and composed of a haphazard admixture of chondroid and adipose elements showing no features of atypia or malignancy. 

Pulmonary hamartoma should be distinguished from Pulmonary chondroma, which is associated with Carney Triad and are composed only of cartilage and bone with a peripheral fibrous pseudocapsule and lack adipose, smooth muscle and entrapped pulmonary elements, which may be seen in pulmonary hamartomas. 

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Case information

rID: 43935
Published: 30th Mar 2016
Last edited: 26th Oct 2019
System: Chest
Inclusion in quiz mode: Included

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