Pulmonary mucormycosis

Case contributed by Keshaw Kumar
Diagnosis certain

Presentation

Right upper limb weakness.

Patient Data

Age: 80 years
Gender: Male

Portable AP chest x-ray

x-ray

Well-defined round opacity in the right upper zone with an area of relative transradiancy.

HRCT thorax

ct

There is a well-defined mass with thick peripheral consolidation (atoll/reversed halo sign) in the apical segment of the right upper lobe with cavitation in the area of relative central transradiancy (bird's nest sign).

Gas foci are also seen in the soft tissue of the adjacent chest wall and cervical spinal canal through the intervertebral foramen.

CT-guided biopsy

ct

CT guided biopsy from right upper lobe lesion.

Histopathological report

Photo

Specimen title: CT guided core needle biopsy from right upper lobe lesion.

Gross findings: Received grey-white needle biopsy largest measuring 1 x 0.1 cm.

Microscopic findings: Sections show pulmonary tissue. Alveoli are filled with acute inflammatory cell exudate admixed with fibrin. Also noted are multiple broad hyphae of the mucosa.

Impression: Mucormycosis with acute pneumonitis.

Case Discussion

Initially it was thought that his right upper limb weakness was due to a stroke, however both a CT brain and a subsequent MRI brain were normal. The routine CXR revealed an unexpected right apical mass and CT demonstrated the typical bird’s nest appearance. Invasion of the spine and chest wall in the region of the brachial plexus satisfactorily explains his right upper limb weakness. The patient was found to have uncontrolled diabetes mellitus (HbA1c-14%), a risk factor for mucormycosis due to impaired immune function.

Co-authors: Dr Neeraj Bharti (internal medicine) and Dr Saket Ballabh (radiodiagnosis)

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