Absent ductus venosus

Agenesis of the ductus venosus (ADV) is a rare fetal vascular anomaly. According to the data obtained from the screening tests performed at 11-14 weeks of pregnancy, its incidence is reported to be 1/2500 (12).


In the literature review on ductus venosus agenesis, Acherman et.al (13) defined five drainage patterns regarding ductus venosus agenesis under two main topics in the case series. These patterns are;

1. The umbilical vein (UV) connected to the systemic venous circulation by way of the portal sinus:

a. Via an abnormal venous channel from the portal sinus to the right atrium 

b. Presumably via hepatic sinusoids to the hepatic veins

2. The umbilical vein bypassed the portal sinus and the liver and connected to the systemic venous circulation via an abnormal venous channel:

a. From the umbilical vein to the right atrium directly or through a dilated coronary sinus

b. From the umbilical vein to the midportion of the inferior vena cava (IVC)

c. From the umbilical vein to the right iliac vein

3. Cutaneous anastomosis (results in the formation of a caput medusa).



The prognosis of fetuses with absent DV diagnosed at 11–13 weeks depends on the measurement of NT thickness, being poor if the NT is increased and good if the NT is normal (12)

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Article Information

rID: 13833
System: Obstetrics
Section: Pathology
Tag: cases
Synonyms or Alternate Spellings:
  • Agenesis of ductus venosus
  • Agenesis of the ductus venosus
  • Ductus venosus agenesis
  • Absence of the ductus venosus
  • Absent ductus venosus (ADV)

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