Citation, DOI, disclosures and article data
Citation:
Knipe H, Bell D, Foley R, et al. Bilateral adrenal gland hyperenhancement. Reference article, Radiopaedia.org (Accessed on 29 May 2023) https://doi.org/10.53347/rID-28497
Bilateral adrenal gland hyperenhancement or intense adrenal enhancement may be a feature of hypotension and forms part of the CT hypoperfusion complex.
Adrenal gland hyperenhancement has been described in pediatric and small adult series or individual cases of hemorrhagic shock, pancreatitis, sepsis and trauma 1-3 but has not been demonstrated in larger series of adult patients with traumatic hypoperfusion 4.
Adrenal gland hyperenhancement has been demonstrated in adult patients, in both intensive care and polytrauma settings, to be associated with an increased risk of mortality 5,6.
Differential diagnosis
- acute adrenal hemorrhage: more commonly right-sided and unilateral with an enlarged adrenal gland and associated changes in the periadrenal fat 2
- 1. Johnson P, Fishman E. American Journal of Roentgenology. 2010;195 (1): . doi:10.2214/AJR.09.4076
- 2. Venkatanarasimha N, Roobottom C. Intense adrenal enhancement: a feature of hypoperfusion complex. AJR Am J Roentgenol. 2010;195 (1): W82. doi:10.2214/AJR.09.3829 - Pubmed citation
- 3. Cheung SC, Lee R, Tung HK et-al. Persistent adrenal enhancement may be the earliest CT sign of significant hypovolaemic shock. Clin Radiol. 2003;58 (4): 315-8. Pubmed citation
- 4. Kanki A, Ito K, Tamada T et-al. Dynamic contrast-enhanced CT of the abdomen to predict clinical prognosis in patients with hypovolemic shock. AJR Am J Roentgenol. 2011;197 (6): W980-4. doi:10.2214/AJR.10.5736 - Pubmed citation
- 5. Schek J, Macht S, Klasen-Sansone J, Heusch P, Kröpil P, Witte I, Antoch G, Lanzman RS. Clinical impact of hyperattenuation of adrenal glands on contrast-enhanced computed tomography of polytraumatised patients. (2014) European radiology. 24 (2): 527-30. doi:10.1007/s00330-013-3050-4 - Pubmed
- 6.Boos J, Schek J, Kröpil P, Heusch P, Heinzler N, Antoch G, Lanzman RS. Contrast-Enhanced Computed Tomography in Intensive Care Unit Patients With Acute Clinical Deterioration: Impact of Hyperattenuating Adrenal Glands. (2017) Canadian Association of Radiologists journal = Journal l'Association canadienne des radiologistes. 68 (1): 21-26. doi:10.1016/j.carj.2016.07.006 - Pubmed
Promoted articles (advertising)