Carcinoid syndrome

Last revised by Henry Knipe on 6 Mar 2025

Carcinoid syndrome refers to a spectrum of symptoms that result from excessive hormone (mainly serotonin) secretion. 

Occurs equally between the sexes, most commonly in the 40-70 year age group 3.

Diarrhea is the most common and earliest symptom, but others include flushing, right heart failure, pain and bronchospasm 4

Carcinoid syndrome can occur as a paraneoplastic syndrome in the context of a neuroendocrine tumor, most commonly arising from the small bowel ref. The presence of the carcinoid syndrome often indicates hepatic metastatic disease ref.

Cases and figures

  • Case 1
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