Cogan syndrome

Cogan syndrome is a rare vasculitis of children and young adults which primarily characterised by 1,4,6:

However, it can potentially affect a multitude of other organs (classically aortitis) 4.

Aetiology

The exact aetiology is not well known although an autoimmune aetiology has been postulated. 

The onset of the disease is usually rapid with ocular findings preceding tinnitus and vertigo. If untreated the majority of patients will become deaf and 5% will be blind. Aortitis and aortic insufficiency develop in 10-15% of patients. Prognosis is good in patients without symptoms of aortitis and early steroid treatment may prevent deafness 6.

It was initially described by David Glendenning Cogan, American ophthalmologist (1908-1993) in 1945 5.

Share article

Article information

rID: 10385
Section: Syndromes
Tags: cases, eye
Synonyms or Alternate Spellings:
  • Cogan's syndrome

Support Radiopaedia and see fewer ads

Updating… Please wait.
Loadinganimation

Alert accept

Error Unable to process the form. Check for errors and try again.

Alert accept Thank you for updating your details.