Aortitis refers to a general descriptor that involves a broad category of infectious and non-infectious conditions where there is inflammation (i.e. vasculitis) of the aortic wall.
Clinical presentation
The presentation is non-specific with fever, pain and weight loss.
Pathology
Etiology
-
infectious
- syphilitic aortitis
- tuberculous aortitis
- pyogenic aortitis: especially Salmonella infection
- aortitis due to HIV
- infected (mycotic) aortic aneurysm
-
non-infectious
- giant cell arteritis
- Takayasu arteritis
- other rheumatologic disorders
- rheumatoid arthritis
- systemic lupus erythematosus
- granulomatosis with polyangiitis
- Behçet disease
- polyarteritis nodosa
- microscopic polyangiitis
- HLA-B27–associated seronegative spondyloarthropathies
- Cogan syndrome
- chronic periaortitis
- idiopathic aortitis
- radiation-induced aortitis
- IgG4-related cardiovascular disease
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