Knipe H, Sharma R, Haouimi A, et al. Cutaneous and subcutaneous metastases. Reference article, Radiopaedia.org (Accessed on 25 Feb 2025) https://doi.org/10.53347/rID-48216
Cutaneous and subcutaneous metastases are not uncommon, occurring in ~5% (range 0.7-10.4%) of internal malignancies, and representing 2% of skin cancers. The Sister Mary Joseph nodule is a well known cutaneous metastasis.
Pathology
These metastases can come from hematogenous or lymphatic spread, or may result from seeding from a surgical procedure. Underlying primary malignancies include 1,2:
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