There is an autosomal dominant inheritance in the FAP gene (chromosome 5q) in a majority of patients but with 20% of cases resulting from new mutations. Extracolonic features often precede the diagnosis of colonic polyps.
1. Robbins SL, Kumar V, Abbas AK et-al. Robbins and Cotran pathologic basis of disease. W.B. Saunders Company. (2010) ISBN:1416031219. Read it at Google Books - Find it at Amazon
2. Hirokawa M, Manabe T, Hino K. Ampullary carcinoma in Gardner's syndrome: case report. Jpn. J. Clin. Oncol. 1988;18 (1): 43-50. Jpn. J. Clin. Oncol. (link) - Pubmed citation
3. Newman CA, Reuther WL, Wakabayashi MN et-al. Gastrointestinal case of the day. Gardner syndrome. Radiographics. 19 (2): 546-8. Radiographics (full text) - Pubmed citation
4. Wolf J, Järvinen HJ, Hietanen J. Gardner's dento-maxillary stigmas in patients with familial adenomatosis coli. (1986) The British journal of oral & maxillofacial surgery. 24 (6): 410-6. doi:10.1016/0266-4356(86)90054-9 - Pubmed
5. Pereira DL, Carvalho PA, Achatz MI, Rocha A, TardinTorrezan G, Alves FA. Oral and maxillofacial considerations in Gardner's syndrome: a report of two cases. (2016) Ecancermedicalscience. 10: 623. doi:10.3332/ecancer.2016.623 - Pubmed
{"current_user":null,"inclusions":[{"imageId":8603044,"studyId":32191,"caseSlug":"gardner-syndrome","caption":"Case 1: duodenal polyps and osteomas, proven syndrome","thumbnail":"https://prod-images-static.radiopaedia.org/images/8603044/b928e8cf09d2cd4f08c96da2630246_big_gallery.jpeg","isStack":false,"diagnosticCertainty":"confirmed_substantiated"},{"imageId":30373972,"studyId":59476,"caseSlug":"gardner-syndrome-2","caption":"Case 2: multiple osteomas and supernumerary teeth","thumbnail":"https://prod-images-static.radiopaedia.org/images/30373972/4d42640adabe44d244711fd2aa7f5d_big_gallery.jpeg","isStack":true,"diagnosticCertainty":"confirmed_substantiated"},{"imageId":35475097,"studyId":64971,"caseSlug":"gardner-syndrome-3","caption":"Case 3","thumbnail":"https://prod-images-static.radiopaedia.org/images/35475097/b929e5b122f6a7e21202e20e81d1b1_big_gallery.jpeg","isStack":true,"diagnosticCertainty":"confirmed_unsubstantiated"},{"imageId":51825998,"studyId":83526,"caseSlug":"gardner-syndrome-5","caption":"Case 4: after total colectomy","thumbnail":"https://prod-images-static.radiopaedia.org/images/51825998/fa6cf3cbe1dba9af1391826b6af28f_big_gallery.jpeg","isStack":true,"diagnosticCertainty":"confirmed_unsubstantiated"}],"ddx_inclusions":[],"lang":"us"}
Updating… Please wait.
Unable to process the form. Check for errors and try again.