Gastrointestinal schwannoma

A gastrointestinal schwannoma is an extremely rare mesenchymal neoplasm which arises in relation to the gastrointestinal tract.

They are reported to typically present at about the 3rd to 5th decades of life 4.

Patients are often asymptomatic but may occasionally present with abdominal discomfort or upper gastrointestinal bleeding from overlying mucosal ulceration.

Although they arise from Schwann cells of the gastrointestinal wall neural plexa 4, they are considered to be distinctively different from the conventional schwannomas that arise in soft tissue or the central nervous system in terms of histological features.

Location
  • stomach: 60-70% of cases (commonest location)
  • colon: next commonest location
  • rectum
Markers

S100 protein is strongly positive 1,6

CT
  • typically seen as a well-defined, rounded, mural mass(es) with homogeneous attenuation 2
  • tends to lack cystic change and haemorrhage
MRI

Reported features include 4 :

  • T1: low or intermediate signal
  • T1 C+ (Gd): may demonstrate slow but relative uniform enhancement
  • T2: high signal

They are benign tumours and carries a much better prognosis compared with gastrointestinal stromal tumours.

Initially reported by Daimaru et al in 1988 1

Share Article

Article Information

rID: 10659
Tag: cases
Synonyms or Alternate Spellings:
  • Gastrointestinal tract neurinoma
  • Gastrointestinal tract neurilemmoma

Support Radiopaedia and see fewer ads

Updating… Please wait.
Loadinganimation

Alert accept

Error Unable to process the form. Check for errors and try again.

Alert accept Thank you for updating your details.