- represents ~6% of osteosarcomas 3
- 60% in males
- has an older onset (~30 years) and a peak incidence: 30-40 years
- gnawing pain and swelling in the mandible and maxilla
- sessile gingival swelling
- 60% are osteoblastic
- 34% are fibroblastic
- <10% chondroblastic
Described features include:
- cortical involvement
- soft-tissue extension
- intramedullary bone extension
- matrix calcification
Treatment and prognosis
Treatment plan generally includes preoperative chemotherapy followed by surgical excision and postoperative chemotherapy.
Osteosarcoma of the mandible has a more favourable prognosis than that of the maxilla.
History and etymology
The term gnathic is from the Greek word gnathos "γνάθος" meaning jaw.
In general, differential diagnoses include:
- 1. Resnick D, Kransdorf M. Bone and joint imaging. Saunders. ISBN:0721602703. Read it at Google Books - Find it at Amazon
- 2. www.oxforddictionaries.com. in English:. Read relevant article. Accessed on 05/04/2016
- 3. George A, Mani V. Gnathic osteosarcomas: Review of literature and report of two cases in maxilla. J Oral Maxillofac Pathol. 2011;15 (2): 138-43. doi:10.4103/0973-029X.84476 - Free text at pubmed - Pubmed citation