Lingual thyroid

A lingual thyroid is a specific type of ectopic thyroid and results from the lack of normal caudal migration of the thyroid gland.

The condition is congenital and there is a female predilection 1-3.

Many patients are asymptomatic and the diagnosis is made incidentally either as a result of imaging the tongue or attempting to image the thyroid and noting that it is absent.

In symptomatic patients the lingual mass may result in dysphagia, bleeding from mucosal ulceration, or even airway obstruction (more common in infants) 1-2.

Direct examination may reveal a nodular red mass of variable size, ranging from a few millimetres to 3-4 cm 2.

A lingual thyroid results from failure of the normal caudal migration of the thyroid from foramen caecum down to its normal location anterior to the larynx and upper trachea. Thyroid tissue may be found anywhere along the course of the thyroglossal duct, however, complete arrest with thyroid tissue located at the base of the tongue is most common and represents 90% of all cases of ectopic thyroid 1-2. Microscopic deposits of thyroid tissue along its route of descent have been identified in up to 10% of the population, representing small amounts of tissue being 'left behind' during normal development 2.

The thyroid tissue is normal histologically and functionally.


Thyroid function tests are either normal (majority of patients) or demonstrate variable states of hypothyroidism (up to a third of patients) 2.


Ultrasound is only of use in demonstrating absent thyroid tissue in the normal location, which is the case in the majority of cases 1. Only occasionally do patients have thyroid tissue both at the tongue base and elsewhere in the neck.


CT demonstrates are hyperdense soft tissue mass, of the same attenuation as normal thyroid tissue. It is hyperdense on account of the accumulation of iodine within the gland 1,3.

Following contrast administration, the entire gland demonstrates prominent homogeneous enhancement (again just like the normal thyroid gland). There are occasional case reports of inhomogeneous contrast enhancement 5.


Usually seen as a well-defined mass with no invasive features.

Signal characteristics
  • T1: iso to hyperintense to muscle 1,3,6
  • T2: can vary from hypo to iso to hyperintense to muscle 3,6
  • T1C+ (Gd): homogeneous contrast enhancement
Nuclear medicine

A thyroid scan is excellent at not only confirming the diagnosis but also identifying the presence of any thyroid tissue elsewhere in the neck.

Often no treatment is required. In cases where surgical excision is being contemplated, it is essential to establish if there is any normal thyroid tissue elsewhere (usually not the case) as removal of the lingual thyroid will in most cases render the patient profoundly hypothyroid 2.

Carcinoma of a lingual thyroid has been reported but is very rare, presumably no higher than normal thyroid.

A general differential for a posterior midline neck mass includes 3:

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Article information

rID: 9567
System: Head & Neck
Section: Anatomy
Synonyms or Alternate Spellings:
  • Lingual thyroid tissue
  • Lingual thyroid tissues
  • Lingual thyroid gland
  • Lingual thyroid glands

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Cases and figures

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    Figure 1: thyroid migration route (diagram)
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    Nm Thyroid Scan
    Case 1
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    Sublingual thyroi...
    Case 2
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    Lingual thyroid
    Case 3
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    Lingual thyroid
    Case 3
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    Axial - with cont...
    Case 4
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    Case 5: with multinodular goitre
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    Case 6
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