Longitudinally extensive spinal cord lesion

Longitudinally extensive spinal cord lesions (LESCL), also known as longitudinally extensive transverse myelitis (LETM), represent extensive involvement of the spinal cord, with abnormal T2 signal traversing at least three vertebral body segments in length.

Differential diagnosis

They are typical of neuromyelitis optica (NMO) but can be seen in a number of other conditions, including 1-3:

White matter disorders
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Article information

rID: 26463
Section: Gamuts
Synonyms or Alternate Spellings:
  • Longitudinaly extensive spinal cord lesion (LESCL)
  • LESCL
  • Longitudinal extensive transverse myelitis
  • LETM

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Cases and figures

  • Case 1: NMO
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  • Case 2: neurosarcoidosis
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  • Case 3: neuromyelitis optica
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  • Case 4: systemic lupus erythematosus
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