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Macroglossia means an enlarged tongue. It may be absolute (greater than the 95th centile) or relative (enlarged compared with oral cavity).

Recognized associations include:

In rare situations macroglossia can present in an adult, with associations including:

Antenatally, macroglossia is best appreciated on a midline sagittal facial view as a protrusion between the upper and lower lips. To satisfy the diagnosis, the tongue should remain outside the mouth regardless of swallowing movements of lips.

If swallowing is impaired, there may be also evidence of polyhydramnios.

Clinically the tongue may appear relatively large with a small oral cavity or a floor of mouth, e.g. micrognathia.

The tongue may be pushed forward if there is a lesion posteriorly such as:

Article information

rID: 13574
Tag: cases
Synonyms or Alternate Spellings:
  • Enlarged tongue
  • Enlarged fetal tongue
  • Large tongue
  • Enlarged tongues

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