Dr Craig Hacking and Dr T Menezes et al.

Medulloepitheliomas are rare, highly malignant, primitive embryonic tumour derived from the primitive medullary plate and neural tube. It is essentially a tumour of childhood with the age of onset between 6 months and 5 years.


Medulloepitheliomas are classified as embryonal tumours in the WHO classification of CNS tumours 3

Radiographic features

On non-contrast CT scan, the lesion is either isodense or hypodense with variable heterogeneity and calcification. The tumour enhances with contrast.

Treatment and prognosis

Medullary epithelioma carries dismal prognosis with a median survival of 5 months. On the other hand, medulloepitheliomas occurring in the eye or the orbit generally benefit from a gross-total resection and may present a good prognosis. 

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rID: 32419
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