Neonatal neuroblastoma

Last revised by Dr Jeremy Jones on 16 Mar 2019

Neonatal neuroblastoma is a type of congenital neuroblastoma, an embryonal tumor arising from the sympathetic nervous system. In the majority of cases (45%), the tumor is localized in the adrenal gland. 


Neonatal neuroblastoma accounts for less than 5% of all cases and carries a favorable prognosis, with most cases being low/intermediate risk for metastatic disease and recurrence.

Clinical presentation

Around 20% of neonatal neuroblastomas present with spinal cord compression due to intraspinal tumor extension. 

Catecholamines are within normal limits or only slightly elevated in cases of neonatal neuroblastoma.


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