Phthisis bulbi

Dr Ian Bickle and A.Prof Frank Gaillard et al.

Phthisis bulbi, also known as end-stage eye, is an atrophic scarred and disorganised globe that may result from a variety of severe ocular insults. 

The globe is reduced in size (usually <20 mm) with a thickened/folded posterior sclera. Dystrophic calcification is common, and osseous metaplasia sometimes occurs, forming what is called "intraocular bone". 

Causes of this end-stage damage include:

The globe is non-functioning, thus the patient is blind in that eye. Enucleation +/- prosthesis insertion is performed if there is associated chronic pain or for cosmetic reasons.

The differential includes other causes of calcification of the globe.

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Article information

rID: 1871
Section: Gamuts
Tag: orbit
Synonyms or Alternate Spellings:
  • end-stage eye

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Cases and figures

  • Case 1
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  • Case 2: coronal
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  • Case 2: axial
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  • Case 3
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  • Case 4
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  • Case 5: on left
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  • Case 6
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  • Case 7: on plain film - left eye
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  • Case 8: bilateral
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