Rosenthal fibres

Dr Henry Knipe and Dr Yuranga Weerakkody et al.

Rosenthal fibres are astrocytic cytoplasmic inclusions, typically found in areas of longstanding gliosis. These elongated or "corkscrew" structures occur within astrocytic processes and are brightly eosinophilic (stain bright pink on the H&E stain) 1-3. They represent astrocytic processes swollen with glial filaments and amorphous granular material 3

They can be seen in a number conditions, all of which have prominent fibrillary gliosis. Such conditions include 1,3

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Article information

rID: 9211
Section: Pathology
Synonyms or Alternate Spellings:

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    Figure 1: H&E stain 40x
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