Sjögren syndrome (thoracic manifestations)

Thoracic manifestations of Sjögren syndrome are common and sometimes detected before the syndrome diagnosis.

For a broad discussion on the syndrome and its typical lymphocytic infiltration of the exocrine glands, please refer to the main article on Sjögren syndrome

Patients usually present with chronic dry cough and dyspnoea.

Pathogenesis of the pulmonary involvement in patients with Sjögren syndrome is not clearly understood. Studies have shown an important role of epithelial cells and B-cell hyperactivation as part of the mechanism of this involvement 1

Pulmonary histologic features are diverse and different patterns of interstitial pneumonia or airway abnormalities are commonly seen in the same patient. 

For the lung lymphoproliferative disorders, considerations should include: 

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Article information

rID: 47955
System: Chest
Synonyms or Alternate Spellings:
  • Pulmonary manifestations of Sjögren syndrome
  • Sjögren syndrome: pulmonary manifestations
  • Thoracic manifestations of Sjögren syndrome

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Cases and figures

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    Case 1: with lymphocytic interstitial pneumonia
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