Solitary ill-defined osteolytic lesion (differential)
Citation, DOI, disclosures and article data
Citation:
Mudgal P, Bell D, Murphy A, et al. Solitary ill-defined osteolytic lesion (differential). Reference article, Radiopaedia.org (Accessed on 29 Mar 2025) https://doi.org/10.53347/rID-27009
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rID:
27009
Article created:
17 Jan 2014,
Prashant Mudgal
Disclosures:
At the time the article was created Prashant Mudgal had no recorded disclosures.
View Prashant Mudgal's current disclosures
Last revised:
Disclosures:
At the time the article was last revised Daniel J Bell had no recorded disclosures.
View Daniel J Bell's current disclosures
Revisions:
9 times, by
7 contributors -
see full revision history and disclosures
Systems:
Sections:
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Synonyms:
- Ill defined lytic lesions
- Lytic lesions in bone
- Differential diagnosis of a solitary ill defined osteolytic lesions
Ill-defined solitary osteolytic lesions can be caused by following entities 1:
- intraosseous hemangioma
- chondroblastoma
- osteoblastoma
- giant cell tumor
- fibrosarcoma of bone
- malignant fibrous histiocytoma
- chondrosarcoma
- osteosarcoma
- Ewing sarcoma
- angiosarcoma
- multiple myeloma
- bone metastasis
- bone lymphoma
- Langerhans cell histiocytosis
- hemophilic pseudotumor
- osteonecrosis (bone infarct)
- osteomyelitis
- skeletal sarcoidosis
References
- 1. Burgener FA, Kormano M, Pudas T. Differential Diagnosis in Conventional Radiology. Thieme. (2008) ISBN:1588902757. Read it at Google Books - Find it at Amazon
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Cases:
- Multiple myeloma
- Solid variant of the aneurysmal bone cyst (ABC)
- Osteosarcoma
- Renal cell carcinoma - bone metastasis
- Brown tumors compressing the spinal cord
- Ewing's sarcoma of scapula
- Langerhans cell histiocytosis of fibula
- Fungal osteomyelitis
- Thyroid cancer metastasis to bone
- Ewing sarcoma
- Periosteal osteosarcoma
- Giant cell tumour of bone - maxilla
Related articles: Bone tumours
The differential diagnosis for bone tumors is dependent on the age of the patient, with a very different set of differentials for the pediatric patient.
-
bone tumors
- bone-forming tumors
- cartilage-forming tumors
- bizarre parosteal osteochondromatous proliferation (Nora lesion)
- chondroblastoma
- chondromyxoid fibroma
- chondrosarcoma
- enchondroma
- juxtacortical chondroma
- osteochondroma
- fibrous bone lesions
- bone marrow tumors
- other bone tumors or tumor-like lesions
- adamantinoma
- aneurysmal bone cyst
- benign fibrous histiocytoma
- chordoma
- giant cell tumor of bone
- Gorham massive osteolysis
- hemangioendothelioma
- hemophilic pseudotumor
- intradiploic epidermoid cyst
- intraosseous lipoma
- musculoskeletal angiosarcoma
- musculoskeletal hemangiopericytoma
- primary intraosseous hemangioma
- post-traumatic cystic bone lesion
- simple bone cyst
-
skeletal metastases
- morphology
- location
- impending fracture risk
- staging
- approach
- describing a bone lesion
- differentials
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