Citation, DOI, disclosures and article data
Citation:
Weerakkody Y, Baba Y, Sharma R, et al. Yolk sac tumor. Reference article, Radiopaedia.org (Accessed on 17 Feb 2025) https://doi.org/10.53347/rID-147277
Yolk sac tumor (YST), also known as an endodermal sinus tumor, is a type of malignant germ cell tumor.
Epidemiology
Yolk sac tumors usually develop in infants, young children, and young women 1.
Pathology
Yolk sac tumors are non-epithelial tumors of germ-cell origin.
Location
Yolk sac tumors occur at variable sites with the ovary being the commonest.
Serological markers
Yolk sac tumors tend to secrete alpha-fetoprotein (AFP).
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1. Song L, Wei X, Wang D et al. Primary Yolk Sac Tumor Originating from the Endometrium: A Case Report and Literature Review. Medicine (Baltimore). 2019;98(15):e15144. doi:10.1097/MD.0000000000015144 - Pubmed
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2. Ji M, Lu Y, Guo L, Feng F, Wan X, Xiang Y. Endometrial Carcinoma with Yolk Sac Tumor-Like Differentiation and Elevated Serum β-HCG: A Case Report and Literature Review. Onco Targets Ther. 2013;6:1515-22. doi:10.2147/OTT.S51983 - Pubmed
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3. Iscar T, Arean C, Chiva L, Sanz J. Ovarian Yolk Sac Tumor. Int J Gynecol Cancer. 2021;31(5):797-8. doi:10.1136/ijgc-2021-002538 - Pubmed
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4. Wang Y, Yang J, Yu M et al. Ovarian Yolk Sac Tumor in Postmenopausal Females: A Case Series and a Literature Review. Medicine (Baltimore). 2018;97(33):e11838. doi:10.1097/MD.0000000000011838 - Pubmed
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