Brain metastases from breast cancer

Case contributed by Qutaiba Jaf'ar Mahmoud
Diagnosis certain

Presentation

Headache and altered level of consciousness.

Patient Data

Age: 35 years
Gender: Female
This study is a stack
Axial
T1
This study is a stack
Coronal
T2
This study is a stack
Axial
T2
This study is a stack
Axial
FLAIR
This study is a stack
Axial
DWI
This study is a stack
Axial
ADC
This study is a stack
Axial
Gradient Echo
This study is a stack
Axial T1
C+ fat sat
This study is a stack
Sagittal
T1 C+
This study is a stack
Coronal
T1 C+
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Info

There are innumerable variable-sized intra-axial brain lesions seen in both cerebral, cerebellar hemispheres and left pons with their epicenter close to the grey-white matter junction. They show hypointense signal on T1, hyperintense signal on T2 with hyperintense perilesional edema of variable amounts and intense post-contrast ring enhancement with facilitated diffusion in the center of the lesions.

The largest lesion appears lobulated and is seen in the right frontal lobe with significant perilesional vasogenic edema causing mass effect upon the corpus callosum and the frontal sulci, which appear effaced, resulting in subfalcine herniation. Pending right-sided uncal herniation is noted.

Case Discussion

This patient has an established history of metastatic breast cancer. The features are highly suggestive of brain metastases.

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