Anaplastic astrocytoma NOS

Case contributed by Dr Juan José Gómez Muga


Subacute cognitive decline. Dizziness.

Patient Data

Age: 65 years
Gender: Male

Hypodense left hemispheric lesion with mass effect. Midline shift, sulcal effacement and right lateral ventricle effacement. No enhancement with contrast.


Left temporoinsular lesion with mass effect. High signal on T2 and FLAIR sequences. No diffusion restriction. In the lateral margin there is a focal area of enhancement with increased rCBV on perfusion weighted images.

Case Discussion

Stereotactic biopsy was performed. Histology confirmed the diagnosis of anasplastic astrocytoma (WHO grade III).

Note: IDH mutation status is not provided in this case and according to the current (2016) WHO classification of CNS tumours, this tumour would, therefore, be designated as an anaplastic astrocytoma NOS.

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Case information

rID: 48770
Published: 23rd Oct 2016
Last edited: 29th Sep 2017
Tag: tumor
Inclusion in quiz mode: Included

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