L-asparaginase induced pancreatitis in childhood acute lymphoblastic leukemia
Diagnosis almost certain
Presentation
Background of childhood acute lymphoblastic leukemia, with elevated amylase and lipase.
Patient Data
Age: 10 years
Gender: Male
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Info
Enlarged pancreas and peripancreatic fluid in the lesser sac and left pararenal space.
Case Discussion
L-asparaginase has been part of the treatment of childhood onset ALL for many decades now. L-asparaginase induced pancreatitis is known to be a major complication of this treatment, but the pathophysiology behind this is still to be found.
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