Morphology of abnormal nodes in rectal cancer (illustration)

Case contributed by Niharika Praveen
Diagnosis not applicable

Abnormal rectal cancer nodes

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These morphologic criteria assess whether locoregional lymph nodes may be involved in rectal cancer.

Original work of Niharika Praveen.

Case Discussion

In rectal cancer, high resolution MRI can be used for staging.

For tumors above the dentate line, the short axis of nodes in the mesorectal, superior rectal and inferior mesenteric territories is measured.

Three morphologic criteria are also assessed 1:

  • heterogeneity/irregularity of signal

  • irregularity of border

  • round shape

The determination of whether nodes are involved by disease or not is made as follows:

  • >9mm in short axis diameter = suspicious

  • 5-9mm in short axis diameter and meet 2 out of 3 criteria = suspicious

  • <5mm and meet all 3 criteria = suspicious

Following chemoradiotherapy, nodes measuring greater than 5 mm in short axis diameter are considered to be suspicious.

Note that these criteria do not apply to internal iliac or obturator nodes, which are considered as locoregional but have different size thresholds. They also do not apply to external iliac, common iliac. paraaortic and inguinal nodes (for tumors above the dentate line); these are considered metastatic (M).

Case uploaded with assistance from Dr Vikas Shah.

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