Alternating radiolucent and radiodense metaphyseal lines

Last revised by Mohammad Taghi Niknejad on 29 Nov 2022

Alternating radiolucent and radiodense metaphyseal lines can be seen with a number of conditions and the differential diagnosis is wide:

See also

Cases and figures

  • Case 1: OI and bisphosphonate lines
  • Case 2: osteopetrosis
  • Case 3: bisphosphonate therapy
  • Case 4: bisphosphonate therapy - osteogenesis imperfecta
  • Case 5: osteopetrosis
  • Case 6: zebra stripe sign

Imaging differential diagnosis

  • Radiolucent metaphyseal line in leukemia
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