Osteogenesis imperfecta and bisphosphonate lines

Case contributed by Dr Michael Sargent

Patient Data

Age: 10 months
Gender: Female

Osteopaenic, gracile bones with zebra stripes. Evidence of prior right femoral fracture. 

Case Discussion

Baby girl with type II osteogenesis imperfecta, treated with cyclical bisphosphonate therapy (pamidronate) resulting in the "zebra stripe sign". Also note the wormian bones on the skull x-ray.

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Case information

rID: 6037
Published: 10th Apr 2009
Last edited: 13th Aug 2019
Inclusion in quiz mode: Included

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