Osteogenesis imperfecta and bisphosphonate lines
Citation, DOI, disclosures and case data
At the time the case was submitted for publication Michael Sargent had no recorded disclosures.
View Michael Sargent's current disclosuresPatient Data
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Osteopaenic, gracile bones with zebra stripes. Evidence of prior right femoral fracture.
Zebra stripes from cyclical bisphosphonate therapy.
Lateral x-ray of the skull shows wormian bones.
Case Discussion
Baby girl with type II osteogenesis imperfecta, treated with cyclical bisphosphonate therapy (pamidronate) resulting in the "zebra stripe sign". Also note the wormian bones on the skull x-ray.
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