Calcifying pulmonary metastases are rare. These should not be confused with metastatic pulmonary calcification.
Calcification in metastases can arise through a variety of mechanisms: bone formation in tumors osteoid origin, calcification and ossification of tumor cartilage, dystrophic calcification and ossification of tumor cartilage, dystrophic calcification and mucoid calcification.
A number of primary malignancies can potentially cause calcification. The reported spectrum includes metastatic nodules from 3:
- mucinous type carcinomas
- thyroid cancer
- treated metastatic choriocarcinoma
- giant cell tumor of the bone
A useful mnemonic to remember the various causes can be found here.
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