Cerebral blood flow (CBF)

Cerebral blood flow (CBF) is one of the parameters generated by perfusion techniques (CT perfusion and MR perfusion). CBF is defined as the volume of blood passing through a given amount of brain tissue per unit of time, most commonly milliliters of blood per minute per 100g of brain tissue 1.

In most instances cerebral blood flow is difficult to measure in absolute terms, and relative CBF (rCBF) is calculated instead; relative to normal white matter. 

Quantitative CBF (qCBF) can be estimated using specific techniques, and varies significantly between white and grey matter (roughly twice as high in grey vs white matter)  2

  • grey matter: ~50 +/- 15 ml/100g/min *
  • white matter: 22 +/- 5 ml/100g/min

* these are rounded figures as differences exist between techniques and publications


MRI physics
Share article

Article Information

rID: 43779
Section: Physics
Synonyms or Alternate Spellings:
  • CBF

Support Radiopaedia and see fewer ads

Updating… Please wait.
Loadinganimation

Alert accept

Error Unable to process the form. Check for errors and try again.

Alert accept Thank you for updating your details.