- low to absent B-cells
- T-cell mediated defects
- CD4 T-cell lymphopenia
- inverted CD4/CD8+ T-cell ratio
Patients with Good syndrome are highly susceptible to bacterial infections. Radiologically, patients with a thymoma may present with findings compatible with immunodeficiency, such as chronic lung disease.
History and etymology
Good syndrome was first described by Robert "Bob" Alan Good, (1922-2003) 7 an American immunologist, in 1955 4-6.
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- 7. Robert A. Good May 21, 1922–June 13, 2003. (2003) The Journal of Immunology. 171 (12): 6318. doi:10.4049/jimmunol.171.12.6318 - Pubmed