Haemangiopericytoma is a term formerly used to describe a continuum of mesenchymal tumours with elevated cellularity found throughout the body in soft tissue and bone. After many years of controversy, haemangiopericytomas have been shown to not only share histological features similar to solitary fibrous tumours but also similar genetic alteration: genomic inversion of 12q13 locus resulting in fusion of NAB2 and STAT6 genes, the latter expressed and able to be assessed using immunohistochemistry techniques 4.

As a result, systemically the term "haemangiopericytoma" is no longer routinely used. In the central nervous system, because the appearances of haemangiopericytomas and solitary fibrous tumours are quite different, the distinction has been somewhat kept; in the most recent WHO classification of CNS tumours (2016 update to 4th edition) meningeal haemangiopericytoma and solitary fibrous tumour of the dura are considered the one entity 4

History and etymology

The term was first used by the American pathologists Arthur Purdy Stout and Margaret Ransone Murray in 1942 to describe a soft tissue tumour presumably of pericytic origin, with a monomorphic population of compact polygonal or fusiform cells and a branching stromal vascular pattern with a "staghorn" form 3,4

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Article information

rID: 1436
System: Vascular
Tag: cases
Synonyms or Alternate Spellings:
  • Hemangiopericytoma
  • Haemagiopericytomas
  • Hemagiopericytoma
  • Hemagiopericytomas
  • Hemangioperictyoma - general
  • Haemangioperictyoma - general
  • Cellular solitary fibrous tumor
  • Cellular SFT
  • Solitary fibrous tumor, hemangiopericytoma type

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Cases and figures

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    Pulmonary angiogr...
    Case 1: pleural solitary fibrous tumour
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    Case 2: meningeal haemangiopericytoma
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