Meandering main pancreatic duct

Last revised by Henry Knipe on 20 Mar 2025

Meandering main pancreatic duct denotes a main pancreatic duct that drains normally into the major papilla but performs a hairpin turn (reverse Z-type) or loop (loop-type) in the pancreatic head, in contradistinction to the smooth curvature seen in most cases.

Their exact incidence is not known.

These ductal variants are found on ERCP and MRCP studies.

Significantly increased incidence of meandering pancreatic duct has been reported in patients with idiopathic recurrent acute pancreatitis (40%) compared with the general population (2.2%) 1.

Cases and figures

  • Figure 1: loop-type
  • Figure 2: reverse-Z type
  • Case 1: meandering main pancreatic duct
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