Staphyloma is the term given to an eye whose scleral-uveal coats are stretched with uveal protrusion. This most commonly occurs posteriorly, although anterior staphyloma also is recognised. As opposed to coloboma, staphyloma defect is located off-center from the optic disc, typically temporal to the disc 3.

Clinical presentation

Patients often present with severe axial myopia 3.


It is an acquired defect secondary to weakness and thinning of the scleral-uveal coats 3.

Posterior staphyloma
  • progressive myopia (or mega myope) is the most common cause
  • glaucoma
  • scleritis
  • necrotizing infection
  • surgery/trauma
  • radiotherapy
Anterior staphyloma

Seen secondary to inflammation or infection of the sclero-corneal lining of the eye. 

Radiographic features

  • increased eye size
  • focal deformity (not as marked as coloboma), usually posterior
  • non-enhancing uveo-sclera

Differential diagnosis

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Article Information

rID: 4009
Synonyms or Alternate Spellings:
  • Staphylomas
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    Figure 1: chart - causes of increased eye size
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    Case 1
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    Case 2
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    Case 3: posterior staphyloma
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    Case 4
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