Colpocephaly

Colpocephaly is a descriptive term to a disproportionate prominence of the occipital horns of the lateral ventricles. It can result from a wide range of congenital insults.

Patient may present with motor abnormalities, cognitive deficit, visual abnormalities, and seizures. 

Associated conditions

Radiologically, diagnosis of colpocephaly becomes more likely when posterior horn to anterior horn ratio of the lateral ventricle (P/A ratio) is ≥ 3 2.

P/A ratio also helps to distinguish colpocephaly from the normal pressure hydrocephalus, which is an important differential diagnosis. 

The term comes from the Greek: kolpos (hollow) and kephalos (head); and it was coined by the neurologist Paul Ivan Yakovlev and the neuropathologist Richard C. Wadsworth in 1946 1,3.

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Article information

rID: 9590
Section: Gamuts
Tag: refs
Synonyms or Alternate Spellings:
  • Colpocephalic brain

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Cases and figures

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    Callosal dysgenes...
    Case 1: with dysgenesis of corpus callosum
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    Case 2: with agenesis of the corpus callosum
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    Case 3
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    Note the left cho...
    Case 4: with concurrent lissencephaly spectrum
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    T2 FLAIR AXIAL
    Case 5
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    with agenesis of corpus callosum
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