An intraosseous ganglion (plural: ganglia) is a benign subchondral radiolucent lesion without degenerative arthritis.
Tends to occur in middle age.
Patients may have mild localized pain.
They are uni-/multilocular cysts surrounded by a fibrous lining, containing gelatinous material.
- mucoid degeneration of intraosseous connective tissue perhaps due to trauma/ischemia
- penetration of juxtaosseous soft-tissue ganglion (=synovial herniation) into underlying bone (occasionally)
Common locations are:
- epiphyses of long bones (medial malleolus, femoral head, proximal tibia, carpal bones)
- subarticular flat bone (acetabulum)
Typically well-demarcated solitary lytic lesion, with a sclerotic margin. No communication with joint can be demonstrated.
- solitary, unilocular or multilocular 2
- usually sclerotic rim is present
Bone scans demonstrate increased radiotracer uptake (in 10%).
- post-traumatic/degenerative cyst
- 1. Dähnert W. Radiology review manual. Lippincott Williams & Wilkins. (2007) ISBN:0781738954. Read it at Google Books - Find it at Amazon 2. Perdikakis E, Skiadas V. MRI characteristics of cysts and "cyst-like" lesions in and around the knee: what the radiologist needs to know. Insights Imaging. 2013;4 (3): 257-72. doi:10.1007/s13244-013-0240-1 - Free text at pubmed - Pubmed citation