Lacrimal gland
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View Tariq Walizai's current disclosures- Lacrimal glands
The lacrimal gland lies in the superolateral aspect of the orbit. It is part of the lacrimal apparatus and is responsible for tear production.
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Gross anatomy
The lacrimal gland is roughly almond-sized and located anteriorly in the superolateral aspect of the extraconal space of the orbit. It has two lobes, a larger orbital lobe that extends deep into the orbital septum and a smaller palpebral lobe. Its orbital lobe sits in the lacrimal fossa of the orbit on the lateral margin of the levator palpebrae superioris muscle.
The lacrimal gland measures ~14.5 mm in axial length, 18 mm in coronal length and ~4.5 mm sagittal length (thickness). The size of the lacrimal gland decreases with age 1. Its cellular structure is similar to the salivary glands but it is unique in that it is composed of both epithelial and lymphoid tissues 2,3.
It drains via many small ducts into the lateral aspect of the superior conjunctival fornix.
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Arterial supply
lacrimal artery, an orbital branch of the ophthalmic artery supplies the gland
Venous drainage
lacrimal tributaries draining to the superior ophthalmic vein
Innervation
Secretomotor parasympathetic fibers via the greater petrosal nerve synapse in the pterygopalatine ganglion. Postganglionic fibers continue into the orbit via the zygomatic nerve which anastomoses with the lacrimal nerve.
Lymphatic drainage
Lymphatics of all the orbital structures drain to the preauricular and parotid lymph nodes through the eyelids and cheeks.
Related pathology
-
bilateral enlargement 2,3
IgG4 disease
-
malignancy
lymphoma
leukemia
histiocytosis
-
unilateral enlargement 2
-
malignancy
adenocarcinoma
infection
-
History and etymology
"Lacrima" is the Latin word for "a tear". Some speculate that the Latin word may have derived from a copyist's error writing λακρύ instead of δάκρυ ("dacro"), the Greek word for "a tear".
The gland was originally noted by Galen but was more thoroughly described in 1574 by Caracanus of Milan, a student of Fallopius. In 1662, N Stensen demonstrated that tears were formed by the gland and did not originate in the brain, as previously thought.
References
- 1. Tamboli D, Harris M, Hogg J, Realini T, Sivak-Callcott J. Computed Tomography Dimensions of the Lacrimal Gland in Normal Caucasian Orbits. Ophthalmic Plast Reconstr Surg. 2011;27(6):453-6. doi:10.1097/IOP.0b013e31821e9f5d - Pubmed
- 2. Hughes G & Miszkiel K. Imaging of the Lacrimal Gland. Semin Ultrasound CT MR. 2006;27(6):476-91. doi:10.1053/j.sult.2006.09.002 - Pubmed
- 3. Mohan S, Hegde A, Tchoyoson Lim C. Lacrimal Glands: Size Does Matter!. Middle East Afr J Ophthalmol. 2011;18(4):328-30. doi:10.4103/0974-9233.90140 - Pubmed
- 4. Izumi M, Eguchi K, Uetani M et al. MR Features of the Lacrimal Gland in Sjögren's Syndrome. AJR Am J Roentgenol. 1998;170(6):1661-6. doi:10.2214/ajr.170.6.9609194 - Pubmed
- 5. Warner M, Weber A, Jakobiec F. Benign and Malignant Tumors of the Orbital Cavity Including the Lacrimal Gland. Neuroimaging Clin N Am. 1996;6(1):123-42. - Pubmed
- 6. Origin of Medical Terms. (1961) ISBN: 0028523903 - Google Books
- 7. Keith L. Moore, Arthur F. Dalley, A. M. R. Agur. Clinically Oriented Anatomy. (2013) ISBN: 9781451119459 - Google Books
- 8. Last, R. J., McMinn, R. M. H.. Last's Anatomy, Regional and Applied. (1994) ISBN: 044304662X - Google Books
Incoming Links
- Mikulicz syndrome
- Küttner tumour
- Orbital lymphoma
- Ocular globe
- Capillary haemangioma of the orbit
- Adenoid cystic carcinoma
- Dacryops
- Adnexa (disambiguation)
- Superior salivary nucleus
- Parasympathetic ganglia in the head and neck
- Superior ophthalmic vein
- Lacrimal apparatus
- Lacrimal artery
- Panda sign (sarcoidosis)
- Nasolacrimal drainage apparatus
- Orbital inflammatory disease (differential)
- Lacrimal gland prolapse
- Bogorad syndrome
- Lacrimal canaliculi
- Subconjunctival fat prolapse
- Dacryops
- Recurrent dacryoadenitis
- Graves ophthalmopathy
- Ocular rupture
- Orbitotomy and Graves ophtalmopathy
- Orbitotomy and Graves ophtalmopathy
- Pleomorphic adenoma of lacrimal gland
- Dacryocystitis and dacryocystocele
- Medial canthus foreign body
- Idiopathic orbital inflammation
- Subperiosteal abscess of the orbit
- Basal cell carcinoma of the eyelid
- Nonspecific orbital inflammation
- Adenoid cystic carcinoma of lacrimal gland
- Adenoid cystic carcinoma of lacrimal gland
- Dermoid cyst of the lacrimal gland
- Orbital roof blow-in fracture
- Optic nerve sheath meningioma
- Ocular tear and foreign body
- Graves ophthalmopathy
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