Lacrimal gland

The lacrimal gland lies in the superolateral aspect of the orbit. It is part of the lacrimal apparatus and is responsible for tear production. 

The lacrimal gland is roughly almond-sized and located anteriorly in the superolateral aspect of the extraconal space of the orbit. It has 2 parts, a larger orbital part that extends deep into the orbital septum and a smaller palpebral part. Its orbital part sits in the lacrimal fossa of the orbit on the lateral margin of the levator palpabrae superioris muscle.

The lacrimal gland measures ~14.5 mm in axial length, 18 mm in coronal length and ~4.5 mm sagittal length (thickness). The size of the lacrimal gland decreases with age 1. Its cellular structure is similar to the salivary glands but it is a unique in that it is composed of both epithelial and lymphoid tissue 2,3.

It drains via many small ducts into the lateral aspect of the superior fornix.

The lacrimal artery, an orbital branch of the ophthalmic artery supplies the gland. Venous drainage is via lacrimal tributaries draining to the superior ophthalmic vein.

Secretomotor parasympathetic fibres via the greater petrosal nerve synapse in the pterygopalatine ganglion. Postganglionic fibres continue into the orbital via the zygomatic nerve which anastomoses with the lacrimal nerve

Lymphatics of all the orbital structures drain to the preauricular and parotid lymph nodes through the eyelids and cheeks.

See lacrimal gland masses.

  • bilateral enlargement 2,3
    • sarcoidosis
    • malignancy
      • lymphoma
      • leukaemia
    • histiocytosis
  • unilateral enlargement 2
    • malignancy
      • adenocarcinoma
    • infection

"Lacrima" is the Latin word for "a tear". Some speculate that the Latin word may have derived from a copyist's error writing λακρύ instead of δάκρυ ("dacro"), the Greek word for "a tear".

The gland was originally noted by Galen, but was more thoroughly described in 1574 by Caracanus of Milan, student of Fallopius. In 1662, N Stensen demonstrated that tears were formed by the gland and did not originate in the brain, as previously thought.

Head and neck anatomy
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Article information

rID: 29360
System: Head & Neck
Section: Anatomy
Synonyms or Alternate Spellings:
  • Lacrimal glands

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Cases and figures

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    Image 1: Gray's anatomy - lacrimal apparatus
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