Lytic skull lesion
Last revised by Rania Adel Anan
on 16 Oct 2022
Citation, DOI, disclosures and article data
Citation:
Anan R, Ibrahim D, Glick Y, et al. Lytic skull lesion. Reference article, Radiopaedia.org (Accessed on 26 Feb 2025) https://doi.org/10.53347/rID-19581
Permalink:
rID:
19581
Article created:
Disclosures:
At the time the article was created Jeremy Jones had no recorded disclosures.
View Jeremy Jones's current disclosures
Last revised:
16 Oct 2022,
Rania Adel Anan
Disclosures:
At the time the article was last revised Rania Adel Anan had no financial relationships to ineligible companies to disclose.
View Rania Adel Anan's current disclosures
Revisions:
11 times, by
10 contributors -
see full revision history and disclosures
Systems:
Sections:
Synonyms:
- Lytic skull lesions
- Lytic calvarial lesions
- Lytic calvarial lesion
Lytic skull lesions have a relatively wide differential that can be narrowed, by considering if there are more than one lesion and whether the mandible is involved.
Pathology
Causes
- lytic skeletal metastases
- multiple myeloma
- epidermoid - scalloped border with a sclerotic rim
- eosinophilic granuloma - Langerhans cell histiocytosis
- hemangioma
- Paget disease (osteolytic phase)
- osteomyelitis
- plasmacytoma
- lacunar skull (craniolacunae, Lückenschädel)
- pacchionian granulation
- vascular markings
- sarcoidosis
- burr hole craniotomy
- calvarial doughnut lesion
Mnemonic: MEL TORME
References
- 1. Burgener FA, Kormano M, Pudas T. Differential Diagnosis in Conventional Radiology. Thieme. (2008) ISBN:1588902757. Read it at Google Books - Find it at Amazon
- 2. Lucie Colas, Sabine Caron, Anne Cotten. Skull Vault Lesions: A Review. (2015) American Journal of Roentgenology. doi:10.2214/AJR.14.13415
- 3. Lorenzo Ugga, Renato Cuocolo, Sirio Cocozza, Andrea Ponsiglione, Arnaldo Stanzione, Vito Chianca, Alessandra D’Amico, Arturo Brunetti, Massimo Imbriaco. Spectrum of lytic lesions of the skull: a pictorial essay. (2018) Insights into Imaging. 9 (5): 845. doi:10.1007/s13244-018-0653-y
- 4. Carrie K. Gomez, Scott R. Schiffman, Alok A. Bhatt. Radiological review of skull lesions. (2018) Insights into Imaging. 9 (5): 857. doi:10.1007/s13244-018-0643-0
- 5. Lytic lesions of the skull – differential diagnosis. doi:10.1594/ecr2014/C-2064
Incoming Links
Articles:
Cases:
- Lytic bone lesions due to multiple myeloma with pathologic intertrochanteric fracture
- Multiple myeloma
- Intradiploic epidermoid cyst
- Arachnoid granulation
- Skull metastasis
- Langerhans cell histiocytosis
- Arachnoid granulation
- Intradiploic epidermoid cyst
- Malakoplakia with multisystem involvement
- Langerhans cell histiocytosis
- Multiple myeloma
- Multiple myeloma - orbit
- Skull metastases from breast cancer