Lytic skull lesion

Last revised by Rania Adel Anan on 16 Oct 2022

Lytic skull lesions have a relatively wide differential that can be narrowed, by considering if there are more than one lesion and whether the mandible is involved.

Pathology

Causes

Mnemonic: MEL TORME

Cases and figures

  • Case 1: multiple myeloma
  • Case 2: Langerhans cell histiocytosis
  • Case 3: lacunar skull
  • Case 4: epidermoid cyst
  • Case 5: Eosinophilic granuloma
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