Metastatic pulmonary calcification

Metastatic pulmonary calcification (MPC) is a form of pulmonary calcification where there is calcium deposition in normal lung pulmonary parenchyma. 

Causes

It can occur in a variety of benign and malignant disorders such as:

Distribution

Metastatic pulmonary calcification is typically most marked in the upper lobes. This is thought to be due to higher ventilation to perfusion ratio in apices hence less CO2 pressure and more alkaline environment.

CT

It is usually characterised by centrilobular fluffy ground-glass nodular opacities that may or may not appear calcified. Very rarely ring like calcification may be seen 5.

Nuclear medicine
Bone scan

Increase uptake in pulmonary opacities is confirmatory. 

Overall prognosis will depend on the underlying cause.

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Article information

rID: 21366
System: Chest
Synonyms or Alternate Spellings:
  • Non-malignant metastatic pulmonary calcification
  • Metastatic pulmonary calcifications
  • Metastatic lung calcification
  • Metastatic lung calcifications

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Cases and figures

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    Case 2
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    Calciphylaxis and...
    Case 3
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    Case 4: right lower lobe
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