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Necrosis (plural: necroses) is defined as unregulated cell death. This is in contrast to apoptosis, which is a form of regulated, or programmed, cell death 1.
Necrosis is the most common type of cell death observed in injury/disease. It occurs when cellular damage is so severe that lysosomal enzymes enter the cytoplasm, causing autodigestion of the cell 1.
The main types of necrosis are:
- 1. Vinay Kumar, Abul K. Abbas, Jon C. Aster. Robbins and Cotran Pathologic Basis of Disease. (2014) ISBN: 9780323266161