Necrosis
Citation, DOI, disclosures and article data
Citation:
Rich J, Bell D, Elfeky M, Necrosis. Reference article, Radiopaedia.org (Accessed on 02 Dec 2024) https://doi.org/10.53347/rID-73854
Permalink:
rID:
73854
Article created:
28 Jan 2020,
Justin Rich
Disclosures:
At the time the article was created Justin Rich had no recorded disclosures.
View Justin Rich's current disclosures
Last revised:
Disclosures:
At the time the article was last revised Daniel J Bell had no recorded disclosures.
View Daniel J Bell's current disclosures
Revisions:
5 times, by
3 contributors -
see full revision history and disclosures
Sections:
Synonyms:
- Necroses
Necrosis (plural: necroses) is defined as unregulated cell death. This is in contrast to apoptosis, which is a form of regulated, or programmed, cell death 1.
Necrosis is the most common type of cell death observed in injury/disease. It occurs when cellular damage is so severe that lysosomal enzymes enter the cytoplasm, causing autodigestion of the cell 1.
The main types of necrosis are:
- coagulative: tissue architecture is preserved
- liquefactive: loss of tissue architecture, formation of liquid/pus
- caseous: most common with tuberculosis; friable, structure less cell debris
- fat necrosis: refers to local areas of fat destruction, commonly encountered in pancreatitis 1
References
- 1. Vinay Kumar, Abul K. Abbas, Jon C. Aster. Robbins and Cotran Pathologic Basis of Disease. (2014) ISBN: 9780323266161
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